广东医学2013，Vol.34Issue(7)：1044-1046,3.
T1～3期胃癌术中前哨淋巴结活检的意义
The clinical significance of sentinel lymph node biopsy in T1～3 gastric cancer
摘要
Abstract
Objective To investigate the successful detection rate and accurate rate of sentinel nodes ( SLN ) in T1-3 gastric cancer. Methods Intraoperative lymphatic mapping and SLN biopsy ( SLNB ) with methylene blue were performed in 98 patients with T1-3 gastic cancer, who received subsequent standard radical gastrectomy with lymphadenecto-my ( D2 or D3 ). The successful detection rate and accurate rate of SLN were assessed. Results According to pathological diagnosis, T1 , T2 and T3 gastric cancer were revealed in 16, 46 and 36 cases, respectively. Stained nodes were detected in 90 cases ( success rate: 91.8% ). Thirty - nine cases were found with lymph node metastasis; among whom metastasis in both SLN and non - SLN, SLN alone or non - SLN alone were revealed in 18 , 12 and 9 cases, respectively. The successful detection rates were 96. 8% in T1-2 group and 83. 3% in T3 group, with accurate rates of 98. 3% and 73. 3% , respectively. Conclusion SLNB accurately predicts the lymph node metastatic status in T1-2 gastric cancer patients, routine lymph node dissection can avoid unnecessary D2 surgery in negative sentinel lymph node metastasis. In T3 group, SLNB can find abnormal lymph flow, providing intraoperative lymph node navigation.关键词
胃癌/病理学/前哨淋巴结活检Key words
gastric neoplasms/ pathology/ sentinel lymph node biopsy引用本文复制引用
黄建豪,吴智勇,王少洪,张仕义..T1～3期胃癌术中前哨淋巴结活检的意义[J].广东医学,2013,34(7):1044-1046,3.基金项目
广东省汕头市重点科技计划项目(编号:汕科府[2010]63号-24) （编号:汕科府[2010]63号-24）
