摘要
Abstract
Objective To explore the clinical value and observe the clinical efficacy of hypertonic saline for capillary bronchitis in infants by aerosol inhalation.Methods 89 infants with capillary bronchitis hospitalized into the pediatric ward of our hospital from Oct.2010 to Oct.2012 were selected and randomly divided into two groups.On the basis of general conventional treatment,the treatment group was given aerosol inhalation of 2 ml hypertonic saline(3％ NaC1) and 2.5 mg salbutamol,and the control group was dealt with aerosol inhalation of 2 ml saline(0.9％ NaC1) and 2.5 mg salbutamol.Aerosol inhalation was used in both groups by air compression atomizing oxygen driven pumps Q8h until hospital discharge.Compared the remission time of gasp and cough,the time of pulmonary rales disappeared and the score changes of the clinical illness severity before and after treatment.Results The remission time of gasp and cough,the time of pulmonary rales disappeared and the time of hospitalization in treatment group were (3.31 ± 1.13) days,(4.61 ± 0.72) days,(3.84 ± 1.22) days,and (5.75 ± 1.40)days,respectively,which were significantly shorter than those of the control group ([4.50 ± 0.94],[5.93 ± 1.11],[5.15 ± 1.31],[6.81 ± 1.64] days),with significant differences between the two groups (P＜0.01).The scores of the clinical illness severity in treatment group after 1st,2nd,3rd,and 4th day's treatment were(5.88 ± 0.78)points,(5.01 ± 0.59)points,(4.13 ± 0.68) points,and(3.59 ± 0.70)points,respectively,which were lower than those of the control group([6.95-± 0.82],[6.36 ± 0.84],[5.57 ± 0.64],[4.45 ± 0.83] points),with significant differences between the two groups (P＜0.01).No serious atomization-relative adverse reactions (acute bronchospasm,decrease in blood oxygen saturation,etc) occurred in both groups.Conclusions The efficacy of aerosol inhalation of hypertonic saline for the capillary bronchitis infants is significantly better than that of saline.What' s more,aerosol inhalation of hypertonic saline is an effective and safe treatment,which can decrease the scores of the clinical illness severity in infants,obviously shorten the time of hospitalization and have no obvious adverse reactions.关键词
毛细支气管炎/高渗盐水/雾化吸入/婴幼儿/治疗Key words
Bronchitis/ Hypertonic saline/ Aerosol inhalation/Infants/ Cure
