国际医药卫生导报2013，Vol.19Issue(8)：1113-1115,3.DOI:10.3760/cma.j.issn.1007-1245.2013.08.022
小儿下呼吸道感染肺炎链球菌耐药性分析
Drug resistance analysis on streptococcus pneumoniae from lower respiratory tract infection in children patients
黄诚花 1李林祖 1莫伟雄 1吕波 1何俊君 1黄天然1
作者信息
摘要
Abstract
Objective To learn about the drug resistance condition of streptococcus pneumoniae in children patients in our hospital.Methods We analyzed the drug resistance status of streptococcus pneumoniae isolated in children' s sputum for 3 consecutive times from Jan 2010 to Jan 2012.The disc diffusion method (K-B method) was used,the results of susceptibility testing was according to NCCL200 version control quality control standard of judgment,judging intermediary,resistance and sensitive.Statistical analysis used SPSS 13.0 statistical software,data of each group was compared with Chi-squared methods.Results All strains were sensitive to vancomycin,followed by levofloxacin (drug resistance rate 3.3％),strains of erythromycin resistance rates was the highest (90.2％),followed by clindamycin (89.3％).Cotrimoxazole,penicillin (82.7％) sensitive rates were on a downward treud.And drug resistance rates of amoxicillin potassium clavulanate,mezlocillin sulbactam,cefuroxime and cefotaxime were 13.1％,16.4％,18.9％ and 19.7％ respectively.Conclusion For pediatric winter respiratory infections,streptococcus was very common especially in infants and young children,early drug use was ineffective and prone to complications,concurrent empyema,lung abscess,pneumonia,myocarditis,and even septic shock,it is necessary to carry out dynamic monitoring in drug resistance of streptococcus pneumoniae to guide clinical selection of antibiotics,to improve the cure rate and reduce complications.关键词
肺炎链球菌/耐药性Key words
Streptococcus pneumoniae/Drug resistance引用本文复制引用
黄诚花,李林祖,莫伟雄,吕波,何俊君,黄天然..小儿下呼吸道感染肺炎链球菌耐药性分析[J].国际医药卫生导报,2013,19(8):1113-1115,3.
