国际医药卫生导报2013，Vol.19Issue(8)：1133-1135,3.DOI:10.3760/cma.j.issn.1007-1245.2013.08.030
促红细胞生成素治疗慢性心力衰竭合并贫血的临床研究
Clinical research on erythropoietin in the treatment of chronic heart failure patients with anemia
摘要
Abstract
Objective To observe the clinical effect and side effects of erythropoietin (EPO) for treating chronic heart failure (CHF) patients with anemia.Methods 81 patients with CHF and anemia were randomly divided into the treatment group (n=40) and the control group (n=41); patients in the control group were given oral treatment of angiotensin converting enzyme inhibitors,digoxin,diuretics,[3 blocker.Patients in treatment group were given subcutaneous injection of EPO on the basis of the treatment for the control group.The clinical results and side effects of the two groups were comparatively analyzed.The course of treatment was 1 year.Results In the two groups,the LVEF,cardiac function,6-min-walking distance,hemoglobin and BNP after treatment were significantly improved,compared with those before treatment (P＜O.05).The results of the treatment group were significantly better than those of the control group (P＜0.05); and the side effects had no obvious difference between the two groups (P＞0.05).Conclusions EPO can improve the heart function indexes in patients with CHF and anemia,and can increase exercise tolerance,but without obvious side effects.关键词
促红细胞生成素(EPO)/慢性充血性心力衰竭(CHF)/贫血Key words
Erythropoietin (EPO)/Chronic heart failure (CHF)/Anemia.引用本文复制引用
钟耀彬,杨伟民,周沛晓,李绍波..促红细胞生成素治疗慢性心力衰竭合并贫血的临床研究[J].国际医药卫生导报,2013,19(8):1133-1135,3.
