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单唾液酸四己糖神经节苷脂钠治疗化疗后末梢神经炎的临床疗效观察

庄少雄 黄瑞红 王永南 张安秦

国际医药卫生导报2013,Vol.19Issue(8):1143-1145,3.
国际医药卫生导报2013,Vol.19Issue(8):1143-1145,3.DOI:10.3760/cma.j.issn.1007-1245.2013.08.034

单唾液酸四己糖神经节苷脂钠治疗化疗后末梢神经炎的临床疗效观察

Observation on clinical curative effect of Monostalotetrahexosylgangliside on peripheral neuritis after chemotherapy

庄少雄 1黄瑞红 1王永南 1张安秦1

作者信息

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摘要

Abstract

Objective To investigate the clinical efficacy of Monostalotetrahexosylgangliside (GM1) in treatment of peripheral neuritis after chemotherapy.Methods 172 cases of peripheral neuritis after chemotherapy were randomly divided into two groups.Treatment group with 86 cases was treated with GM1,40 mg,intravenous infusion,one time a day,until the end of chemotherapy.Control group with 86 patients was treated with vitamin B6 tablets 60 mg,orally,three times a day,until the end of chemotherapy.Two groups were assessed respectively for efficacy.Results The effect of treatment group (80.2 %) was obviously better than that of control group (8.1%).The difference was statistically significant (P<0.05).Conclusions GM1 can relieve peripheral neuritis of breast cancer patients after chemotherapy.

关键词

单唾液酸四己糖神经节苷脂钠/末梢神经炎/化疗

Key words

Monostalotetrahexosylgangliside/Peripheral neuritis/Chemotherapy

引用本文复制引用

庄少雄,黄瑞红,王永南,张安秦..单唾液酸四己糖神经节苷脂钠治疗化疗后末梢神经炎的临床疗效观察[J].国际医药卫生导报,2013,19(8):1143-1145,3.

国际医药卫生导报

1007-1245

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