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血小板反应蛋白与子痫前期的相关性研究

吴惠芬

国际妇产科学杂志2013,Vol.40Issue(2):126-128,133,4.
国际妇产科学杂志2013,Vol.40Issue(2):126-128,133,4.

血小板反应蛋白与子痫前期的相关性研究

Thrombospondin and the Correlation of Preeclampsia

吴惠芬1

作者信息

  • 1. 510182 广州医学院研究生院
  • 折叠

摘要

Abstract

Recently research indicate that an imbalance of maternal circulating pro-and anti-angiogenic factors may play a role in the pathogenesis of preeclampsia. Thrombospondin (TSP) is a protein expressed in various cells such as platelet, endothelial cells,matrix fiber cells,vascular smooth muscle cells,interstitial cells and immunocyte,which acts as a potent antiangiogenic agent. TSP affects several cellular functions,including proliferation,motility,adhesion,apoptosis and infiltrate make the endometrial spiral arterioles vessel tone stricture and rejection, induce placenta blood flow reduce, then induce preeclampsia.

关键词

凝血酶敏感蛋白类/先兆子痫/血管内皮生长因子类/成纤维细胞生长因子

Key words

Thrombospondins/Pre-eclampsia/Vascular endothelial growth factors/Fibroblast growth factors

引用本文复制引用

吴惠芬..血小板反应蛋白与子痫前期的相关性研究[J].国际妇产科学杂志,2013,40(2):126-128,133,4.

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