中医学报2013,Vol.28Issue(5):725-728,4.
血管性认知障碍患者中医证候与认知障碍相关性探讨
Investigation of the Correlation Between Cognitive Impairment and Syndromes of Traditional Chinese Medicine in Vascular Cognitive Impairment
摘要
Abstract
Objective: To investigate the correlation between cognitive impairments and the Chinese medicine syndrome characteristics of vascular cognitive impairment ( VCI). Methods: 127 patients came from both neurology clinic and ward of Hospital of traditional Chinese Medicine of Guangdong province with cerebral vascular disease ( CVD) meeting studying criterion were included, and 35 community cognitively normal elderly as the normal control group were included. The Mini-Mental State Examination ( MMSE) and a neuropsycho-logical battery were used to access the cognitive function; the investigation of syndrome manifestations and the syndrome differentiation scale of vascular dementia (SDSVD) were used for diagnosis of syndrome manifestations, the correlation between MMSE score,the impaired cognitive domains and Chinese medicine syndromes was analyzed. Results:By logistic regression analysis,the syndrome of viscera stagnation and turbid left,the syndrome of deficiency of blood and qi significantly affect the MMSE scores. There was significant relationship between the syndrome of turbid phlegm blocking upper orifices and memory dysfunction, the syndrome of hyperactivity of liver yang due to yin deficiency and attention dysfunction, the syndrome of deficiency of blood and qi and visual spatial impairment. And there was no significant relationship between executive dysfunction and TCM syndrome, language dysfunction and TCM syndrome. Conclusion: There is close relationship between TCM syndrome of VCI and cognitive impairment. If we start from these factors,we can take advantages of Traditional Chinese Medicine on the prevention and treatment of VCI. Reference citation;Zhang Yanhong,Liang Weixiong,Zhu Lei. Investigation of the Correlation Between Cognitive Impairment and Syndromes of Traditional Chinese Medicine in Vascular Cognitive Impairment [ J ]. China Journal of Chinese Medicine, 2013,28(5) : 725 -728.关键词
血管性认知障碍/血管性痴呆/非痴呆型血管性认知障碍/中医证候Key words
vascular cognitive impairment/ vascular dementia/ vascular cognitive impairment no dementia/ traditional Chinese medical syndrome分类
医药卫生引用本文复制引用
张彦红,梁伟雄,朱磊..血管性认知障碍患者中医证候与认知障碍相关性探讨[J].中医学报,2013,28(5):725-728,4.基金项目
国家"十一五"计划科技重大专项(编号:2008ZX09312-021) (编号:2008ZX09312-021)