实用临床医药杂志2013，Vol.17Issue(5)：80-82,3.DOI:10.7619/jcmp.201305025
奥曲肽联合奥美拉唑治疗肝硬化上消化道出血临床观察
Clinical observation on octreotide and omeprazole for treating liver cirrhosis accompanied by upper gastrointestinal hemorrhage
摘要
Abstract
Objective To investigate the clinical effects of octreotide and omeprazole for treating liver cirrhosis accompanied by upper gastrointestinal hemorrhage. Methods Fifty - two patients with liver cirrhosis accompanied by upper gastrointestinal hemorrhage considered as objects of study were randomly divided into observation group and control group, 26 cases in each group. Blood volume of patients in both groups was supplemented. Omeprazole was administered in the control group, while octreotide in the observation group based on the treatment of the treatment group. The clinical effects of patients in both groups were observed, and mean hemostatic time, mean length of hospital stay, reoccurred hemorrhagic rate for 48 h and occurrence of adverse reactions were calculated. Results The total clinical efficacy rate of the observation group was 92.3% , markedly higher than that of the control group (69.2%). Mean hemostatic time and length of hospital stay of the observation group were significantly shorter than those of the control group, while its reoccurred hemorrhagic rate for 48 h obviously lower than that of the control group. Conclusion In the treatment of liver cirrhosis accompanied by upper gastrointestinal hemorrhage, the combination of octreotide and omeprazole has conspicuous clinical effects, with low incidence rate of adverse reactions, which is of great importance in clinical treatment of liver cirrhosis accompanied by upper gastrointestinal hemorrhage.关键词
肝硬化/上消化道出血/奥美拉唑/奥曲肽Key words
liver cirrhosis/ upper gastrointestinal hemorrhage/ omeprazole/ octreotide分类
医药卫生引用本文复制引用
翟攀..奥曲肽联合奥美拉唑治疗肝硬化上消化道出血临床观察[J].实用临床医药杂志,2013,17(5):80-82,3.基金项目
中国高校医学期刊临床专项资金(11320034) （11320034）
