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肾康注射液联合羟苯磺酸钙治疗慢性肾脏病的临床观察

沈皓 罗进辉 童运涛 肖杨 张慧

实用临床医药杂志2013,Vol.17Issue(7):116-117,123,3.
实用临床医药杂志2013,Vol.17Issue(7):116-117,123,3.DOI:10.7619/jcmp.201307042

肾康注射液联合羟苯磺酸钙治疗慢性肾脏病的临床观察

Clinical observation of Shenkang injection combined with calcium dobesilate for chronic kidney disease

沈皓 1罗进辉 1童运涛 1肖杨 1张慧1

作者信息

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摘要

Abstract

Objective To observe the clinical effect of Shenkang injection combined with calcium dobesilate in the treatment of chronic kidney disease (CKD) at the 3rd to 4th phase. Methods Ninety two CKD patients at the 3rd to 4th phase were randomly divided into 3 groups: 30 cases in control group (group A), 31 cases in calcium dobesilate group (group B) and 31 cases in Shenkang injection group (group C). The courses of treatment in 3 groups were all 1 month. The changes of 24 h urine protein quantitation 24 h (24 h UTP), serum creatinine (Scr), urea nitrogen (BUN), uric acid (UA) and cystatin C (CysC) before and after treatment were observed. Results Compared with group A, the levels of 24 h UTP and CysC after treatment in group B both decreased significantly, and the level of 24 h UTP after treatment in group C reduced markedly. The differences in groups A and B showed statistical significance. After treatment, the levels of BUN, UA and CysC in group C were all lower than those in group B notably. Conclusion Shenkang injection combined with calcium dobesilate can effectively decrease the levels of BUN, UA and CysC of CKD patients and delay the declination of renal function, which has a better effect of renal function.

关键词

肾康注射液/羟苯磺酸钙/慢性肾脏病

Key words

Shenkang injection/ calcium dobesilate/ chronic kidney disease

分类

医药卫生

引用本文复制引用

沈皓,罗进辉,童运涛,肖杨,张慧..肾康注射液联合羟苯磺酸钙治疗慢性肾脏病的临床观察[J].实用临床医药杂志,2013,17(7):116-117,123,3.

基金项目

中国高校医学期刊临床专项资金(11320074) (11320074)

实用临床医药杂志

OACSTPCD

1672-2353

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