实用临床医药杂志2013，Vol.17Issue(7)：118-120,3.DOI:10.7619/jcmp.201307043
预防恶性肿瘤患者静脉血栓栓塞症的临床分析
Clinical analysis of venous thromboembolism prevention for patients with malignant tumor
摘要
Abstract
Objective To investigate the clinical methods of venous thromboembolism (VTE) prevention for patients with malignant tumor. Methods Eighty hospitalized patients with malignant tumor were randomly divided into intervention group (n = 60) and control group ( n = 20). The intervention group was intervened according to thrombelastogram and clotting results, whereas the control group was not intervened. According to different hypercoagulable factors, intervention group was further grouped into deep venous thrombosis (DVT) group (group A) , erythro-cyte aggregation group (group B) and erythrocyte aggregation group without thrombosis (group C), 20 cases in each group. DVT in lower limbs, pulmonary thromboembolism (PTE) and occurrence of hemorrhagic events of patients in each group were observed. Results During hospitaliza-tion, both incidences of DVT and fatal PTE in the intervention group were significantly lower than those in the control group. Compared with hemorrhagic events in each group during hospitalization and follow- up visit, all the differences showed no statistical significance.Conclusion For patients with malignant tumor, understanding early clotting changes of thrombosis according to thrombelastogram and clotting presentation and taking positive interventions can effectively reduce the incidence rates of DVT and PTE. Seeking different causal factors based on different hypercoagulable states and applying individual treatment can ensure the efficiency and safety of treatment.关键词
恶性肿瘤/血栓弹力图/高凝状态/血栓形成Key words
malignant tumor/ thrombelastogram/ hypercoagulable states/ thrombosis分类
医药卫生引用本文复制引用
王莉,刘义,高芸菲,孔曼,孔斌,杨建东,黄希芬,裴文仲..预防恶性肿瘤患者静脉血栓栓塞症的临床分析[J].实用临床医药杂志,2013,17(7):118-120,3.基金项目
中国高校医学期刊临床专项资金(11320044) （11320044）
