色谱2013，Vol.31Issue(4)：380-385,6.DOI:10.3724/SP.J.1123.2012.10037
超高效液相色谱-串联质谱法快速测定纺织品和皮革中偶氮染料释放的致癌芳香胺
Determination of carcinogenic aromatic amines derived from azo colorants in textiles and leather by ultra high performance liquid chromatography-tandem mass spectrometry
摘要
Abstract
A rapid determination method was developed for the quantification and confirmation of 22 carcinogenic aromatic amines derived from azo colorants in textiles and leather by ultra high performance liquid chromatography-tandem electrospray ionization mass spectrometry (UHPLC-MS/MS). The methods of EN 14362-1:2012 (for textiles) and ISO 17234-1 :2010 (for leather) were adopted for sample pretreatment, finally diluted with methanol. The target compounds were separated by an Eclipse XDB-C18 RRHD column and eluted with methanol and water in gradient, and then determined by positive electrospray ionization mass spectrometry under multiple reaction monitoring (MRM) mode. The external standard method was used for the quantitative analysis. The separation conditions, fragment voltages, collision energies, etc. were optimized. The limits of quantification (LOQ) were below 0. 2 mg/kg for different compounds , matrix spike recoveries ranged from 70% to 120% at the spiked levels of 500, 1 000 and 1 500 μg/L, and the relative standard deviations (RSDs) were less than 15%. The proposed method is rapid, sensitive, accurate and selective.关键词
超高效液相色谱-串联质谱/致癌芳香胺/偶氮染料/纺织品/皮革Key words
ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) / carcinogenic aromatic amines/ azo colorants/ textiles/ leather分类
化学化工引用本文复制引用
温裕云,欧延,何明超,弓振斌..超高效液相色谱-串联质谱法快速测定纺织品和皮革中偶氮染料释放的致癌芳香胺[J].色谱,2013,31(4):380-385,6.基金项目
福建省自然科学基金重点项目(B0220001) （B0220001）
远东技术服务有限公司委托项目. （）
