Abstract
Objective To investigate the relationship of stroke - associated pneumonia ( SAP ) to post - stroke acute hypertension in elderly patients with ischemic stroke. Methods A total of 134 patients with acute ischemic stroke admitted to this hospital from 2010 to 2011 were divided, based on acute blood pressure values, into groups control ( with normal or mild hypertension, n =65 ), moderate ( with moderate hypertension, n =44 ), severe ( with severe hypertension, n =25 ). At admission all patients had routine blood and biochemical tests, 12 - lead ECG, X - ray, transthoracic echocardiography and brain MRI, and dysphagia examined by pulse oximetry and water gurgle test. The complications including previous histories of stroke, ischemic heart diseases, chronic congestive heart failure, diabetes and hypertension were recorded. Univariate and multivariate Logistic regression analysis was used to analyze the risk factors of SAP. Results There was significant difference in levels of SBP, WBC, CRP and GCS scores and dysphagia incidence between groups SAP and non - SAP ( P <0. 05 ). There was difference in WBC, GCS and incidences of dysphagia and SAP between groups control, moderate and severe ( P < 0. 05 ), thereinto groups moderate and severe were different from control group in GCS scores, dysphagia and SAP incidences ( P < 0. 05 ), severe group from control group in WBC ( P < 0. 05 ). Multivariate undonditional logistic regression found WBC [ OR = 1. 325, 95% CI ( 1.073, 1.811 ), P =0.024 ], serum CRP [ OR = 1.356, 95% CI ( 1.082, 1.914 ), P =0.021 ], GCS score [ OR = 0. 842, 95% CI ( 0. 563 , 0. 924 ), P = 0. 015 ], dysphagia [ OR = 1. 735 , 95% CI ( 1. 154, 2. 761 ), P = 0. 007 ] and hypertension [ OR = 2. 185, 95% CI ( 1. 321, 4. 368 ), P = 0. 003 ] into the regression equation. There was difference in SAP risk between groups severe and control ( P < 0. 05 ), adjusted OR = 2. 747 , 95% CI ( 1. 161, 7. 452 ). Conclusion Post - ischemic - stroke acute severe hypertension, an independent risk factor, is important for SAP prevention and provides some theoretical basis for its treatment and drug choice.关键词
卒中/呼吸道感染/卒中相关性肺炎/高血压Key words
Stroke/ Respiratory tract infection/ Stroke - associated pneumonia/ Hypertension分类
医药卫生
