中国全科医学2013，Vol.16Issue(11)：1213-1215,3.DOI:10.3969/j.issn.1007-9572.2013.04.043
老年高血压患者随诊间收缩压变异性与舒张性心力衰竭的关系研究
Relationship between Visit-to-Visit Variability in SBP and Diastolic Heart Falure in Elderly Hypertensive Patients
摘要
Abstract
Objective To analyze the relationship of visit - to - visit variability in systolic blood pressure ( SBP ) with diastolic heart failure ( DHF ). Methods The follow - up blood pressure ( BP ) of 40 elderly hypertensive patients visiting department of cardiology of this hospital from July 2010 to July 2012 were observed and at the end of follow - ups ventricular septal thickness, left ventricular end - diastolic volume, left ventricular end - systolic volume, left ventricular posterior wall thickness, early diastolic mitral flow velocity ( E ), early diastolic mitral annular velocity ( E' ), carotid intima - media thickness ( IMT ) were determined by color Doppler ultrasound, and serum brain natriuretic peptide ( BNP ) detected, follow - up SBP variation and left ventricular mass index ( LVMI) and E/E' calculated. Taking follow - up SBP standard deviation ( SD ) as BPV indicator, E/E' represented left ventricular diastolic ( LVD ) function. Results The follow - up SBP SD was ( 9 ±4 ) mm Hg, positively correlated with E/E', LVMI, IMT(r= 0.389、 0. 318、 0.512, P<0. 05), BNP negatively with E/E' (r= -0.869, P < 0. 05 ), positively with LVMI, IMT ( r = 0. 582 、 0. 488 , P < 0. 05 ). Multiple linear regression analysis showed that SD and BNP have significant impact on the E/E' ( P < 0. 05 ). Conclusion Follow - up BPV, related to LVD function and independent risk factors of DHF in elderly hypertension patients, can both predict occurrence of DHF.关键词
高血压/利钠肽,脑/心力衰竭,舒张性/危险因素Key words
Hypertension/ Natriuretic peptide, brain/ Heart failure, diastolic/ Risk factors分类
医药卫生引用本文复制引用
曹大平,贾玲,王颖..老年高血压患者随诊间收缩压变异性与舒张性心力衰竭的关系研究[J].中国全科医学,2013,16(11):1213-1215,3.基金项目
河南省卫生厅与郑州大学一附院共建项目 （）
河南省卫生科技创新型人才工程中青年科技创新人才项目(河南省卫生厅4099号) （河南省卫生厅4099号）
河南省卫生厅科技攻关项目(2011020038) （2011020038）
