中国药房2013,Vol.24Issue(12):1110-1111,2.DOI:10.6039/j.issn.1001-0408.2013.12.20
康莱特注射液辅助治疗非小细胞肺癌的疗效观察
Efficacy Observation of Kanglaite Injection for Non-small Cell Lung Cancer
摘要
Abstract
OBJECTIVE: To observe clinical efficacy of Kanglaite injection for non-small cell lung cancer (NSCLC). METHODS: 114 NSCLC patients in our hospital during 2010 - 2011 were selected and divided into treatment group (58 cases) and control group (56 cases). Therapeutic scheme for NSCLC was determined in two groups according to staging of tumor. Treatment group was additionally given Kanglaite injection 100 ml intravenously, qd. A treatment course lasted for 21 d, and two groups both received 2 course of treatment. Shot-term efficacies were evaluated according to evaluation criteria for solid tumor issued by WHO; KPS scoring criteria was adopted for evaluation of quality of life; according to acute and subacute toxicity evaluation criterion for WHO anticancer drug, adverse drug reactions were evaluated. RESULTS: After 2 courses of chemotherapy, the effective rate and disease control rate of treatment group were significantly higher than those of control group; the improvement and stability of life quality in treatment group was better than in control group, and the progress was significantly lower than in control group; adverse drug reactions were lower than in control group (P<0.05). CONCLUSION: Kanglaite injection on NSCLC clinical treatment can play a good role in support.关键词
康莱特注射液/非小细胞肺癌/疗效/安全性Key words
KLT/ Non-small cell lung cancer/ Clinical efficacy/ Safety分类
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陈开杰,巫桁锞,刘晓玲..康莱特注射液辅助治疗非小细胞肺癌的疗效观察[J].中国药房,2013,24(12):1110-1111,2.