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醉椒素脂质体的制备及其理化性质考察

陈玉堂 袁曼 朴军颜 闫淑娟 徐霞

郑州大学学报(理学版)2013,Vol.45Issue(1):73-76,4.
郑州大学学报(理学版)2013,Vol.45Issue(1):73-76,4.DOI:10.3969/j.issn/1671-6841.2013.01.018

醉椒素脂质体的制备及其理化性质考察

Study on Preparation of Kavain Lipsomes and Chemicophysical Propery

陈玉堂 1袁曼 1朴军颜 1闫淑娟 1徐霞1

作者信息

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摘要

Abstract

Kavain lipsomes were prepared and the chemicophysical propery was studied. Kavain lipsomes were prepared by dispersion film-ultrasonication method and the content of kavain was determined by HPLC. The character and partical size of kavain lipsomes were observed. The lipsomes were regular under its microphotograph and the size range was (161 ±5)nm. The surface charge of lipsomes was (2.37 ± 0.2) mV. The encapsulation efficiency of kavain in lipsomes was 77. 09%. No obvious changes were found in the above indexes. The kavain liposome prepared by dispersion film-ultrasonication method was of high encapsulation efficiency and of good stability.

关键词

醉椒素/脂质体/理化性质/包封率

Key words

kavain/ lipsomes/ characterization/ encapsulation efficiency

分类

医药卫生

引用本文复制引用

陈玉堂,袁曼,朴军颜,闫淑娟,徐霞..醉椒素脂质体的制备及其理化性质考察[J].郑州大学学报(理学版),2013,45(1):73-76,4.

郑州大学学报(理学版)

OA北大核心CSTPCD

1671-6841

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