现代检验医学杂志2013，Vol.28Issue(2)：152-153,156,3.DOI:10.3969/j.issn.1671-7414.2013.02.049
急性脑梗死患者血清IL-6与颈动脉粥样硬化的相关性
Correlation between Serum Levels of IL-6 and Carotid Artery Atherosclerosis in Patients with Acute Cerebral Infarction
郁超 1陈彤 1张克霞1
作者信息
- 1. 南通市第一人民医院检验科,江苏南通,226001
- 折叠
摘要
Abstract
Objective To investigate the correlation between serum levels of IL-6 and carotid artery atherosclerosis in patients with acute cerebral infarction (ACI).Methods 38 patients with ACI were assigned as experimental group and 30 healthy people as control group.The serum level of IL-6 was measured,and the carotid plaques and the changes of carotid intimal-medial thickness (IMT) were examined by color doppler ultrasonography.Results The average level of IL-6 was significantly higher in ACI group (24.2±7.9 pg/ml) than that of healthy control group (17.1±8.1 pg/ml) (t= 1.932, P< 0.05).The increased carotid IMT were higher in ACI group than in control group [(1.20±0.34)mm vs(1.03±0.20)mm, t=2.314,P<0.05].In ACI group,IL-6 levels were correlated with carotid IMT (r=0.412, P<0.01) and hs-CRP (r= 0.389,P<0.05).Multiple linear stepwise regression analysis showed that IL-6 was one of the important risk factors in ACI.Conclusion These findings showed IL-6 and Inflammatory reaction are risk predictors in the development of carotid artery atherosclerosis and especially its involvement in the progress of ACI.关键词
急性脑梗死/白细胞介素-6/C-反应蛋白/颈动脉粥样硬化Key words
acute cerebral infarction/ interleukin-6 /C-reactive protein/ carotid atherosclerosis分类
医药卫生引用本文复制引用
郁超,陈彤,张克霞..急性脑梗死患者血清IL-6与颈动脉粥样硬化的相关性[J].现代检验医学杂志,2013,28(2):152-153,156,3.
