中国畜牧兽医2013，Vol.40Issue(4)：238-241,4.
丙泊酚静脉麻醉与安氟醚吸入麻醉在巴马小型猪体外循环中的比较研究
Comparative of Propofol Intravenous Anesthesia and Enflurane Inhalation Anesthesia in Cardiopulmonary Bypass of Bama Minipigs
摘要
Abstract
The assay was aimed to compare of propofol intravenous anesthesia and enflurane inhalation anesthesia in cardiopulmonary bypass of Bama Minipigs. 10 Bama Minipigs, the average into two groups were propofol intravenous anesthesia and enflurane inhalation anesthesia, and in preoperative, operative and postoperative the anesthesia monitoring. After openning breast, whole blood were treated with heparin, then the ascending aorta, superior vena cava and inferior vena cava were intuba-ted respectively, and connected to a cardiopulmonary bypass machine line the CPB. The vital signs, nose temperature (NT) , heart rate (HR), mean arterial pressure (MAP), pH and blood oxygen saturation(SPO2) of each experimental pigs were observe and recorded within before introdution of anesthesia (TO), after induction of anesthesia (T1), immediately before CPB (T2), cooling to 30 ℃ (T3), blocking the aorta former immediate (T4), blocking the aorta 4 min (T5) , start thawing immediate (T6), stop CPB immediate (T7), closed chest immediately after (T8) and drawing tube operation over 10 min (T9). Two groups of weight number of pigs, operation time and anesthesia time all had no significant difference (P>0. 05). Different fluorine ether group restore spontaneous breathing a short time in propofol group (P<0. 05). Compared with the basic val-ue(T0 and T1), the NT, HR and MAP value of the experiment pigs were significantly lower (P<0. C5). But each rooms and in the group SPO2 value and pH were not significant different (P>0. 05). Propofol intravenous anesthesia during the operation should be based on the experimental animals of the reaction conditions appropriate adjustments propofol pump into the concentration; and different fluorine ether inhaled anesthesia during the procedure of smooth, anaeesthetic effect was good, postoperative came quickly, suitable for complicated cases, and the time was long operation.关键词
安氟醚/丙泊酚/巴马小型猪/体外循环Key words
enflurane/propofol/ Bama Minipigs/cardiopulmonary bypass分类
医药卫生引用本文复制引用
陈克研,刁玉刚,金强,王洪乾,姚国泉,张铁铮..丙泊酚静脉麻醉与安氟醚吸入麻醉在巴马小型猪体外循环中的比较研究[J].中国畜牧兽医,2013,40(4):238-241,4.基金项目
国家自然青年科学基金项目(31201758). （31201758）
