摘要
Abstract
OBJECTIVE: To evaluate therapeutic efficacy of Gluma desensitizer for dentine hypersensitivity (DH) systematically, and to provide reference for the selection of treatment regimen for DH. METHODS: Systematic searches of CBM, CNKJ, Pubmed, EMbase and Cochrane Central Register of Controlled Trials databases were performed. Meta-analysis was performed by Review Manager 5.1.2 and Stata 11.0 software. RESULTS: A total of 19 studies were included, involving 3 828 patients. Results of Meta-analysis showed that the immediate effective rate [OR=5.04, 95%CI(3.48,7.31),P<0.01], 1-month effective rate [OR= 3.28, 95%CI(2.23,4.83),P<0.01], 3-month effective rate [OR=5.67, 95%CI(3.12,10.29) ,P<0.01] and 6-month effective rate [OR=4.51, 95%CI(2.36, 7.74) , P<0.01] of Gluma were all higher than those of 75% sodium fluoride. For Gluma vs. Gree-nOrTM, no significant difference was found. CONCLUSION: Gluma desensitizer can effectively relieve DH pain than 75% sodium fluoride but for GreenOrTM. Considering small number of studies for comparison between Gluma and GreenOrTM and low quality of studies included, this conclusion should be interpreted with caution.关键词
牙本质过敏症/Gluma/氟化钠/极固宁/Meta分析Key words
Dentine hypersensitivity/ Gluma/ Sodium fluoride/ GreenOrTM/ Meta-analysis分类
医药卫生
