军事医学2013，Vol.37Issue(5)：329-331,3.DOI:10.7644/j.issn.1674-9960.2013.05.003
健康青年男性急进高原右心功能变化研究
Change in right heart function among healthy young males following rapid accent to high altitude
摘要
Abstract
Objective To investigate the changes in right heart structure and function at different altitudes and time courses among healthy young males following rapid accent to high altitude . Methods Young healthy men who entered the plateau for the first time were randomly selected . Their changes in the relative parameters of the right heart system were measured by the same person at 400 m above sea level, after entering the plateau at an altitude of 3700 m 24 hours later, and a week for short stay , and five days after reaching the level of 4400 m following a short stay of one week. Results Compared with the case at sea level,Tei index, pulmonary vascular resistance (PVR) and mean pulmonary artery pressure (mPAP) were obviously increased (P < 0. 05) 1 day after the young males arrived at highlands while RA and RV were significantly decreased (P<0. 001) ,so did PA and E/Aratio (P <0. 05 ). Compared with the level of 3700 m, E/Aratio was obviously increased (P<0. 05) while RA、RV was obviously decreased (P < 0. 05) ; PA,Tei index,mPAP and PVR did not significantly change (P>0.05)at the level of 4400 m. Conclusion The structure and function of the right heart system of these young healthy men improved significantly after their first arrival at the plateau . There was no significant increase in the right ventricular performance. The right ventricular systolic and diastolic function returned to its level on the plains, indicating that the right heart structure will gradually changed with prolonge residence in the high altitude hypoxia environment. The right ventricular systolic and diastolic function will be better preserved by the adaptation and adjustment mechanism of the body.关键词
急性高原病/右心功能/Tei指数/青年男性Key words
acute mountain sickness / right heart function / Tei index / young males分类
医药卫生引用本文复制引用
刘曦,覃军,高旭滨,于世勇,余洁,李相俊,黄岚..健康青年男性急进高原右心功能变化研究[J].军事医学,2013,37(5):329-331,3.基金项目
国家卫生部卫生行业科研专项基金资助项目(201002012) （201002012）
