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血小板表达的P-选择素对B16细胞分泌血小板源性生长因子的影响

亓翠玲 王丽京 叶杰 郭四美 周秦 韩露 魏波

临床与实验病理学杂志2013,Vol.29Issue(5):540-543,4.
临床与实验病理学杂志2013,Vol.29Issue(5):540-543,4.

血小板表达的P-选择素对B16细胞分泌血小板源性生长因子的影响

Effect of platelet P-selectin on platelet-derived growth factor secreted by B16 cells

亓翠玲 1王丽京 1叶杰 1郭四美 1周秦 1韩露 1魏波2

作者信息

  • 1. 广东药学院血管生物学研究所,广州,510006
  • 2. 中山大学附属第三医院胃肠外科,广州,510630
  • 折叠

摘要

Abstract

Purpose To investigate the effect of platelet P-selectin on platelet-derived growth factor secreted by B16 cells. Methods B16 cells were co-cultured with the platelets of C57 mice and P-selectin knockout mice, then PDGF concentration in the supernatant was detected by ELISA. Result There was no difference of the PDGF concentration secrected by the platelets of C57 mice and P-selectin knockout mice. Conclusion Platelet P-selectin had no significant effect on PDGF secreted by B16 cells.

关键词

血小板/P-选择素/血小板源性生长因子/B16细胞

Key words

platelets/P-selectin/platelet-derived growth factor/B16 cell

分类

医药卫生

引用本文复制引用

亓翠玲,王丽京,叶杰,郭四美,周秦,韩露,魏波..血小板表达的P-选择素对B16细胞分泌血小板源性生长因子的影响[J].临床与实验病理学杂志,2013,29(5):540-543,4.

基金项目

广东省医学科研基金(A2011299),国家自然科学基金(30900764) (A2011299)

临床与实验病理学杂志

OA北大核心CSCDCSTPCD

1001-7399

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