中国全科医学2013，Vol.16Issue(10)：1115-1119,5.DOI:10.3969/j.issn.1007-9572.2013.04.012
脂肪肝相关危险因素的研究
Risk Factors for Fatty Liver Disease
摘要
Abstract
Objective To investigate the risk factors for fatty liver disease. Methods A total of 1 067 cases with complete information in our physical examination center between March 2011 and August 2011 were selected in this study. The age, gender, body mass index, blood pressure, fasting blood glucose, blood lipids, blood uric acid, liver function and routine blood examination results were compared between the fatty liver group and non - fatty liver group using questionnaire survey, physical examination, laboratory test, and abdominal ultrasound examination. Results A total of 430 cases of fatty liver were detected out of 1 067 cases ( 40. 30% ) using abdominal ultrasound examination, including 274 male patients and 156 female patients. The prevalence of fatty liver disease was higher in males than in females ( 47.65% vs. 31.71% ) ( x2=28. 018 , P <0. 01 ) . The prevalence was higher in people with monthly earning ≥3 000 RMB ( 47. 05% , 263/559 ) than in people with monthly earning <3 000 RMB (x2=22. 225 , P <0. 01 ) . The prevalence varied in people with different occupations (x2 =55. 260, P<0. 05 ) . Significant difference was observed between the two groups in diet and living habits, such as fatty food consumption, smoking, alcohol consumption, and exercise ( P < 0. 05 ) . The prevalence of overweight, obesity, glucose metabolism disorder, hypertension, hyperlipidemia, and hyperuricemia was higher in fatty liver group than in non - fatty liver group. Univariate analysis showed that the fatty liver group had significantly higher body mass index, systolic blood pressure, diastolic blood pressure, and uric acid, but significantly lower high - density lipoprotein cholesterol and apolipoprotein A1 than the non -fatty liver group ( P <0. 001 ) . Multiple regression analysis showed that age, gentler, body mass index, systolic blood pressure, diastolie blood pressure, uric acid, apolipoprotein B, apolipoprotein Al , low - density lipoprotein cholesterol, high - density lipoprotein cholesterol, triglycerides, fasting - serum glucose level were risk factors for fatty liver disease ( P < 0. 05 ) . Conclusion Unhealthy lifestyles like smoking, alcohol consumption, fatty food consumption, and lack of exercise , as well as overweight, obesity, hypertension, glucose metabolism disorder, dyslipidemia, and hyperuricemia increase the risks for fatty liver diseases.关键词
脂肪肝/危险因素/代谢综合征/生活习惯Key words
Fatty liver disease/ Risk factors/ Metabolic syndrome/ Life style分类
医药卫生引用本文复制引用
曹男,林连捷,郑长青,林艳,王东旭..脂肪肝相关危险因素的研究[J].中国全科医学,2013,16(10):1115-1119,5.基金项目
辽宁省科学技术基金资助项目(2010225008) （2010225008）
辽宁省博士科研启动基金资助项目(20081048) （20081048）
沈阳市科学技术基金资助项目(F10-205-1-17) （F10-205-1-17）
