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江苏省一起急性胃肠炎爆发的疫情调查

付建光 周明浩 姚萍 闻栋 艾静 祁贤 朱叶飞 鲍昌俊 汤奋扬 祖荣强

中国人兽共患病学报2013,Vol.29Issue(5):509-513,5.
中国人兽共患病学报2013,Vol.29Issue(5):509-513,5.DOI:10.3969/cjz.j.issn.1002-2694.2013.05.018

江苏省一起急性胃肠炎爆发的疫情调查

Investigation of an acute gastroenteritis outbreak in Jiangsu Province

付建光 1周明浩 1姚萍 2闻栋 3艾静 1祁贤 1朱叶飞 1鲍昌俊 1汤奋扬 1祖荣强1

作者信息

  • 1. 卫生部肠道病原微生物重点实验室,江苏省疾病预防控制中心,南京,210009
  • 2. 常州市疾病预防控制中心,常州,231022
  • 3. 湖州市疾病预防控制中心,湖州,313000
  • 折叠

摘要

Abstract

In December 2011, an acute gastroenteritis outbreak affected a primary school in Changzhou City, Jiangsu Province. To understand the characteristics and cause of the disease, the cases were investigated individually based on the standardized epidemiological survey form, the demographic data of cases and the samples were collected at the same time. The nucleic acid of the samples was detected by Real-time RT-PCR. Genotype study was conducted by analyzing the nucleotide sequence of N-S region. Sample from a total of 276 cases of gastroenteritis outbreak from Nov 22 to Dec 13, 2011, involving 264 cases of students (the morbidity was 17.4 %), 5 teachers (4.4%) and 7 parents, were collected for the investigation. The most anal swab samples were norovirus positive, which belonged to GII.12 genotype. Results from comprehensive analysis with clinical characteristics, epidemiological investigation, and laboratory test indicated that this epidemic was an acute gastroenteritis outbreak caused by the norovirus GII.12 type with a probably transmission pattern of vomit-to-mouth.

关键词

胃肠炎/爆发/诺如病毒/基因型

Key words

gastroenteritis/ outbreak/ norovirus/ genotype

分类

医药卫生

引用本文复制引用

付建光,周明浩,姚萍,闻栋,艾静,祁贤,朱叶飞,鲍昌俊,汤奋扬,祖荣强..江苏省一起急性胃肠炎爆发的疫情调查[J].中国人兽共患病学报,2013,29(5):509-513,5.

基金项目

Supported by grants from the Jiangsu Province Health Development Project with Science and Education (Nos.ZX201109 & RC2011084) (Nos.ZX201109 & RC2011084)

中国人兽共患病学报

OA北大核心CSCDCSTPCD

1002-2694

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