渔业科学进展2013，Vol.34Issue(1)：119-125,7.
微胶囊剂型黄芪多糖对刺参生长性能、免疫力及抗病力的影响
Impact of APS microcapsules on growth, immunity and disease resistance of sea cucumber Apostichopus japonicus
摘要
Abstract
The study was conducted to investigate the impact of Astragalus polysaccga- rudes(APS) microcapsules (drug loading 17%) on the growth, nonspecific immune indices and resistance of Apostichopus japonicas against Vibrio splendidus infection. APS microcapsules were added at graded levels (1%, 3%, and 5%) to the basal diet to formulate three practical compound diets. Continuous 35-day feeding trials were carried out on A. japonicus at initial body weight of 22. 0 ± 1. Og. After feeding the diets for 35 days, specific growth rate (SGR) for the 5% treatment was 0. 51%/d, which was significantly higher than the control. The activities of serum acid phosphatase (ACP), superoxide dismutase (SOD), and myeloperoxidase (MPO) increased significantly (P<0. 05) in the 3% treatment. During the experiment these factors were determined at 7-day intervals. The activity of ACP was 11. 2U/100ml at 28d during the experiment (P<0. 05) , the activity of SOD was 63. 3U/ml at 21d (P<0. 05) , and the activity of MPO was 40MPO unit/ml at 21d (P>0. 05). After the feeding trial, a V. splendidus injection challenge was given to the sea cucumbers to test the effects of APS microcapsule. The 3% treatment showed significantly better survival than the control (P<0. 05). It is suggested that supplementation of 3% APS microcapsules has the greatest effects on growth, immunity and disease resistance in A. japonicas against V. splendidus. In addition, there was a direct relationship between the level and time of treatment, and the immunity.关键词
微胶囊/黄芪多糖/刺参/生长/免疫/抗病力Key words
Microcapsule/Astragalus polysaccharide/Apostichopus japonicas/Growth/Immune/Disease resistance分类
农业科技引用本文复制引用
樊英,王淑娴,李天保,许拉,于晓清,叶海斌,刁菁,王勇强..微胶囊剂型黄芪多糖对刺参生长性能、免疫力及抗病力的影响[J].渔业科学进展,2013,34(1):119-125,7.基金项目
山东省农业重大应用技术创新课题(鲁财农指[2010]58号)、海洋公益性行业科研专项经费项目 200905020、山东省科技发展计划项目(2010GHY10501)和山东省优秀中青年科学家科研奖励基金项目(BS2010NY021)共同资助 （鲁财农指[2010]58号）
