中国全科医学2013,Vol.16Issue(13):1487-1489,1492,4.DOI:10.3969/j.issn.1007-9572.2013.05.011
不同病因的肺动脉高压患者肺动脉压力水平研究
Comparison of Pulmonary Artery Pressure Levels in Patients with Pulmonary Hypertension of Different Causes
摘要
Abstract
Objective To analyze and compare the levels of pulmonary artery pressure due to different causes in patients with pulmonary hypertension ( PH ) . Methods The data of 2 240 patients diagnosed with PH were retrospectively analyzed from outpatient department, emergency center and inpatient department of Sichuan provincial people's hospital from January 2006 to December 2010. The levels of pulmonary artery systolic pressure ( PASP ) were analyzed and compared for these patients with different causes. Results The proportion of mild, moderate and severe degree of PASP among the 2 240 patients was 43. 79% ( 981/2 240 ), 37. 41% ( 838/2 240 ) and 18. 80% ( 421/2 240 ) respectively. The level of mean PASP in patients with PH due to pulmonary arterial hypertension, left heart disease, chronic lung disease and/or hypoxia, chronic thromboembolic pulmonary hypertension and miscellaneous factors were respectively ( 60 ± 19 ) mm Hg, ( 52 ± 17 ) mm Hg, (50 ± 13 ) mm Hg, ( 61 ± 13 ) mm Hg and ( 56 ± 14 ) mm Hg, with a statistically significant difference by analysis of variance ( P < 0. 05 ) . The top 3 subtypes of PH which possessed the highest level of PASP were persistent pulmonary hypertension of the newborn being ( 97 ± 6 ) mm Hg, pulmonary hypertension due to congenital heart diseases being ( 72 ±28 ) mm Hg, and idiopathic pulmonary arterial hypertension being ( 67 ± 14 ) mm Hg respectively, with significant difference as compared with other subtypes ( P <0. 05 ) . And the subtypes with lowest level of PASP were PH due to portal hypertension and sleep - disordered breathing, being respectively ( 35 ± 15 ) mm Hg and ( 35 ± 16 ) mm Hg, with significant difference as compared with other subtypes ( P <0. 05 ). Conclusion The degree of pulmonary artery pressure is generally mild to moderate in patients with pulmonary hypertension. The highest -leveled subtypes of PH are persistent pulmonary hypertension of the newborn, pulmonary hypertension due to congenital heart diseases and idiopathic pulmonary hypertension respectively. So the patients with these types of PH should be paid more attention.关键词
高血压/肺性/肺动脉压力/病因/特征Key words
Hypertension, pulmonary/ Pulmonary artery pressure/ Cause/ Characteristic分类
医药卫生引用本文复制引用
郭璐,刘跃建,解郑良,周仲伟,杨阳,陈庆,邹俊..不同病因的肺动脉高压患者肺动脉压力水平研究[J].中国全科医学,2013,16(13):1487-1489,1492,4.基金项目
四川省卫生厅科研项目(090442) (090442)