吕晶 1薛武军 1尹爱萍 1靳引红 1李昭 1毋欣桐1
作者信息
- 1. 710061陕西省西安市,西安交通大学医学院第一附属医院肾脏病医院肾内科
- 折叠
摘要
Abstract
Objective To analyze the effect of volume load on nutrition status in patients receiving peritoneal dialysis ( PD ).Methods A total of 177 patients having received PD for over 3 months were divided, according to degree of edema, into groups A ( n = 110, without edema ), B ( n = 38 , with mild edema ), C ( n = 22, with moderate edema ), D ( n = 7 , with severe edema ).The changes of body weight ( BW ), urine output, amount of ultrafiltration, blood pressure ( BP ), average concentration of dialysate, 24 h protein loss of dialysate, albumin, blood glucose ( BG ), C - reactive protein ( CRP ) were evaluated by subjective global assessment ( SGA ) and the incidences of malnutrition compared in 4 groups.Results No significant difference was noted in age ( P = 0.391 ), dialysis adequacy ( P = 0.135 ), glomerular filtration rate ( P = 0.187 ), urine output ( P =0.204 ) in 4 groups.There was difference in BW increases, amount of ultrafiltration, total amount of liquid, SBP ( P < 0.05 ).D group were higher than groups A, B, C in BW increases, amount of ultrafiltration, SBP, higher than groups A, B in total amount of liquid, 24 h protein loss of dialysate, lower than groups A, B, C in albumin, the difference was significant ( P <0.05 ).D group were higher than groups A, B, C in average concentration of dialysate and BG, the difference was significant ( P <0.05 ), higher in CRP and incidence of malnutrition ( P < 0.05 ).Conclusion Increase of volume load of PD patients leads to rise of BP and deterioration of nutritional status.Microinflammation due to volume overload may be one of the reasons causing malnutrition.Control of volume may improve hypertension and malnutrition, but using high glucose dialysate to increase ultrafiltration may aggravate disorders of glucose metabolism to make it more difficult to control volume.关键词
腹膜透析/容量负荷/营养/微炎症Key words
Peritoneal dialysis/ Volume overload/ Malnutrition/ Micro - inflammation分类
医药卫生
