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评估SPECT测定不同年龄段健康人肾小球滤过率的准确性

麻广宇 邵明哲 陈英茂 陈云爽 徐白萱 田嘉禾 孙雪峰

中国医学装备2013,Vol.10Issue(6):5-8,4.
中国医学装备2013,Vol.10Issue(6):5-8,4.DOI:10.3969/J.ISSN.1672-8270.2013.06.002

评估SPECT测定不同年龄段健康人肾小球滤过率的准确性

Estimate the accuracy of SPECT determination glomerular filtration rate in different age healthy people

麻广宇 1邵明哲 1陈英茂 1陈云爽 2徐白萱 1田嘉禾 1孙雪峰2

作者信息

  • 1. 解放军总医院核医学科,北京,100853
  • 2. 解放军总医院肾内科,北京,100853
  • 折叠

摘要

Abstract

Objective: To estimate the accuracy of SPECT determination glomerular filtration rate in different age healthy groups. Methods: Totally 232 Beijing community health residents were selected as the research subjects. Two-sample method and 99Tcm-DTPA dynamic renal imaging were used for determination of GFR (GFRdt and GFRGates, respectively). GFRdt as the reference standard, compare the accuracy of six different age groups GFRGates which get by SPECT Results: ①There were significant differences between GFRdt and GFRcates on six different age groups. ②GFRGates from Six different age groups were significantly lower than those of GFRdt. The difference in the group of 30-39years between GFRdt and GFRGates is maximum, the mean difference is (-34.26±20.79) ml/(min·1.73m)2. The difference in the group of >70years between GFRdt and GFRGates is minimum, the mean difference is (-23.62± 18.60) ml/(min·1.73m)2. ③GFRdt and GFRgates derived from the group 30-39years had the worst correlation (r=0.42). GFRdt and GFRGates derived from the group >70years had the best correlation (r=0.81). Conclusion: The accuracy of GFR which got by SPECT is poor in 20-49years health group, it is better in >50 years health group, while it is the best in >70 years health group.

关键词

肾小球滤过率/放射性核素显像法/双血浆法/健康人/准确性

Key words

Glomerular filtration rate/ Radionuclide imaging method/ Dual plasma sample method/ Health people/ Accuracy

分类

医药卫生

引用本文复制引用

麻广宇,邵明哲,陈英茂,陈云爽,徐白萱,田嘉禾,孙雪峰..评估SPECT测定不同年龄段健康人肾小球滤过率的准确性[J].中国医学装备,2013,10(6):5-8,4.

基金项目

国家973项目(2013CB530800)"内脏器官衰老与相关老年疾病防治的基础研究" (2013CB530800)

中国医学装备

OACSTPCD

1672-8270

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