中国临床医学2012，Vol.19Issue(5)：467-469,3.
慢性阻塞性肺疾病急性加重患者血清降钙素原变化的临床意义
Application of Procalcitonin in the Monitoring of Bacterial Inflammation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective:To investigate the clinical value of procalcitonin(PCT) in the reasonable use of antibiotics in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: A total of 90 cases of AECOPD caused by bacterial infection were enrolled. The level of PCT, erythrocyte sedimentation rate (ESR) , the level of C - reactive protein (CRP) in the serum, and the number of white blood cells(WBC) in the blood were detected before and after treatment. Results: After treatment, the numbers of cases with PCT concentration ≥0. 25 ng/mL, WBCS≥10×109'/L, ESRS≥20 mm/1 h and CRP≥ 10 mg/L significantly decreased [PCT: 88(97. 8%) vs. 0(0% ) , P<0. 05 ; WBC: 65 (72. 2%) vs. 8(8. 9%), P< 0.05;ESR: 88(97.8%)vs. 20(22. 2%) ,P<0. 05 ;CRP: 86(91.1%)vs. 14( 15. 6%) ,P<0. 05]. Conclusion: PCT can be used as a sensitive indicator in the evaluation of pulmonary inflammation control in the treatment of AECOPD.关键词
慢性阻塞性肺疾病/急性加重期/细菌感染/降钙素原Key words
Chronic obstructive pulmonary disease/ Acute exacerbation/ Bacterial infection/ Procalcitonin分类
医药卫生引用本文复制引用
施国华,施劲东,刘子龙,朱芬,王晓如..慢性阻塞性肺疾病急性加重患者血清降钙素原变化的临床意义[J].中国临床医学,2012,19(5):467-469,3.基金项目
上海市卫生局青年科研项目(编号:2010Y036) （编号:2010Y036）
上海市闵行区科委(编号:2010MWPY4) （编号:2010MWPY4）
