中国临床医学2012,Vol.19Issue(5):536-538,3.
2型糖尿病患者冠状动脉病变的危险因素分析
Risk Factors of Coronary Artery Disease in Patients with Type 2 Diabetes
陈云 1卞华 2高鑫2
作者信息
- 1. 江苏省建湖县第四人民医院内科,江苏建湖,224700
- 2. 复旦大学附属中山医院内分泌科,上海,200032
- 折叠
摘要
Abstract
Objective:To study the dangerous factors of coronary artery disease and the safety of coronary artery CT angiography (CTA) in patients with type 2 diabetes. Methods: A total of 34 subjects selected randomly from type 2 diabetes patients hospitalized in Department of Endocrinology and Metablism, Zhongshan Hospital ,Fudan University from August 2009 to July 2010 who underwent coronary artery CTA were involved in the study. Subjects were divided into two groups according to the number and the narrow degree of coronary artery lesions. The parameters of glucose and lipid metabolism, and renal function before and after the coronary artery CTA examination were compared between the two groups. Results: Duration of diabetes, fasting plasma glucose and HbA1c were higher in coronary artery lesions positive group than those in negative group(P all< 0. 05). Adjusted by gender,age,body mass index (BMI) ,the number of coronary artery lesions was positively correlated with duration of diabetes, fasting plasma glucose, HbA1c and 24h urine protein excretion rate, while it was negatively correlated with plus of C peptide(P all<0. 05). There was no significant difference in serum creatinine before and after the coronary artery CTA examination(P>0. 05). Conclusions: The longer duration and higher HbA1c levels of diabetes, the higher risk of asymptomatic coronary heart disease is , which need to be diagnosed by regular coronary heart disease examination. Coronary artery CTA examination is safe for patients with type 2 diabetes whose renal function is normal.关键词
2型糖尿病/冠状动脉病变/冠状动脉CT血管造影Key words
Type 2 diabetes/ Coronary artery lesions/ Coronary artery CT angiography分类
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陈云,卞华,高鑫..2型糖尿病患者冠状动脉病变的危险因素分析[J].中国临床医学,2012,19(5):536-538,3.