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乳腺癌术后不同方案化疗的临床观察与预后比较

王道亮 许骏 王本忠

安徽医科大学学报2013,Vol.48Issue(7):841-843,3.
安徽医科大学学报2013,Vol.48Issue(7):841-843,3.

乳腺癌术后不同方案化疗的临床观察与预后比较

Clinical study and prognosis of the different adjuvant chemotherapy options in the post-operation of breast cancer

王道亮 1许骏 1王本忠1

作者信息

  • 1. 安徽医科大学第一附属医院乳腺外科,合肥230022
  • 折叠

摘要

Abstract

To retrospectively analyze the toxicity and five year disease-free survival ( DFS ) and overall survival rate ( OS ) of three adjuvant chemotherapy( CEF, TEC and TE ) in 480 cases of axillary lymph node-negative breast cancer patients. The results showed that the incidence of cardiotoxicity was statistically significant ( P < 0. 05 ) in three programs and hematologic toxicity, skin and mucous membrane injury, five-year DFS and OS had no statistical difference. Adjuvant chemotherapy of CEF regimen in low-risk breast cancer patients with axillary lymph node-negative had promising five-year DFS and OS. The chemotherapy regimen containing clitaxel did not show any advantage over other adjuvants, and increase chemotherapy toxicity.

关键词

乳腺癌/辅助化疗/无病生存率/总生存率

Key words

breast cancer / adjuvant chemotherapy/ disease-free survival/overall survival

分类

医药卫生

引用本文复制引用

王道亮,许骏,王本忠..乳腺癌术后不同方案化疗的临床观察与预后比较[J].安徽医科大学学报,2013,48(7):841-843,3.

安徽医科大学学报

OA北大核心CSTPCD

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