北华大学学报（自然科学版）2013，Vol.14Issue(3)：325-328,4.DOI:10.11713/j.issn.1009-4822.2013.03.019
孟鲁司特钠咀嚼片对儿童过敏性哮喘前瞻性研究
A Prospective Study of Montelukast Sodium Chewable Tablets on Allergic Asthma in Children
摘要
Abstract
Objective To investigate the clinical efficacy of montelukast on children with allergic asthma.Method 92 children with allergic asthma were randomly divided into the treatment group (47 cases) and control group (45 cases),the basic treatment of patients in two group were the same,treatment group of children with oral montelukast sodium chewable tablets,the control group were administered the same dose comfort chewable tablets,after 3 months of treatment,follow-up of 6 months whether relapse,related changes in children with EOS,FEV1 and statistics and PEF.Results The clinical effective rate in treatment group was 97.87％,there is statistical significance compared with the control group (P ＜ 0.05),the treatment group in the clinical symptoms improved the situation comparing with the control group,the difference was statistically significant (P ＜ 0.05),two groups of children with pulmonary function indices were improved,but the treatment group improved more significantly than the control group,the difference was statistically significant (P ＜ 0.05),two groups of patients during treatment had no adverse drug reaction injury,the treatment group in the recurrence rate was lower than that in control group.Conclusion Montelukast may be used as adjuvant therapy of allergic asthma in children,and taking safety,effect is significant.关键词
儿童过敏性哮喘/孟鲁司特钠咀嚼片/前瞻性研究Key words
child allergic asthma/montelukast sodium chewable tablets/prospective study分类
医药卫生引用本文复制引用
王庆贤..孟鲁司特钠咀嚼片对儿童过敏性哮喘前瞻性研究[J].北华大学学报（自然科学版）,2013,14(3):325-328,4.基金项目
国家自然科学基金项目(81170415). （81170415）
