北京林业大学学报2013，Vol.35Issue(4)：95-100,6.
植物源挥发物α-蒎烯微胶囊制剂的制备
Preparation of α-pinene microcapsulation
摘要
Abstract
An α-pinene slow-release microcapsule with complex coacervation was prepared with chitosan and Arabic gum as wall materials.The optimal preparation process condition was obtained by applying a single-factor test and orthogonal experiment.The results showed that the concentrations of wall material and Arabic gum were 0.2％ and 3.5％,respectively,emulsifier content was 2.5％,ratio of core and wall material was 1 ∶ 1,reaction temperature was 45 ℃,pH was 4.5,time for coacervation was 60 min and stirring revolutions 770 round/min were the best preparation process conditions.Uniform spherical microcapsules had an average particle size of 5 μm.The encapsulation efficiency and drug loading were up to (51.70 ± 2.5) ％ and (42.11 ± 2.3) ％.The microcapsule can extend releasing time of α-pinene,prolong its activity of time,thus expand its scope of application.关键词
α-蒎烯/复凝聚法/微胶囊/缓释Key words
α-pinene/ complex coacervation / microcapsule/ slow release分类
农业科技引用本文复制引用
王丹,迟德富..植物源挥发物α-蒎烯微胶囊制剂的制备[J].北京林业大学学报,2013,35(4):95-100,6.基金项目
林业公益性行业科研专项(201104069)、黑龙江省重大科技攻关项目(GA09B203-5). （201104069）
