重庆医学2013，Vol.42Issue(17)：1943-1945,1948,4.DOI:10.3969/j.issn.1671-8348.2013.17.006
血管内超声观察急性冠脉综合征非显著狭窄的病变斑块破裂及形态特点
Morphologic features of coronary plaque rupture in acute coronary syndromes without significant angiographic lesion detected by intravascular ultrasound
摘要
Abstract
Objective This study was designed to report the characteristics of the culprit lesion with plaque without significant angiographic stenosis after acute coronary syndromes(ACS) by intravascular ultrasound(IVUS).Methods After ACS,IVUS was performed in 45 patients (44.3 years ± 11.3) without significant angiographic stenosis (31 ± 15 ％).Patient were divided into two groups:Group with plaque rupture(16 patients) and Group without plaque rupture(29 patients).Qualitative analysis defined the type of plaque,and quantitative analysis evaluated plaque plus media area,plaque volume,plaque burden,and arterial remodeling index.Results All patients with rupture showed soft or mixed plaque,In group with plaquerupture,plaque rupture was associated with a larger plaque burden[(48.6 ± 8.7) ％ vs (38.5 ± 11.8) ％,P＜0.000 5],a more significant plaque plus media area[(7.2 ± 2.6)mm2 vs (5.1±2.4)mm2,P＜0.001],a greater plaque volume[(154.6±101.4)mm3 vs (96.2±82.1)mm3,P＜0.03],and a higher ratio of plaque volume over length[(8.0±4.1)mm3/mm vs (5.9±3.7)mm3/mm,P＜0.003].In group with plaquerupture,positive remodeling was more frequent than negative remodeling(P＜0.005).In group with plaquerupture,there was no significant difference between the two types of remodeling.Conclusion The plaque ruptures responsible for ACS frequently appear on voluminous plaques with a large plaque burden and positive arterial remodeling.关键词
急性冠状动脉综合征/血管内超声/动脉重构/斑块破裂Key words
acute coronary syndrome/ intravascular ultrasound / arterial remodeling/ plaque rupture引用本文复制引用
周华,王娟,何晓燕,庄少伟,来晏,姚义安,刘学波,汪程..血管内超声观察急性冠脉综合征非显著狭窄的病变斑块破裂及形态特点[J].重庆医学,2013,42(17):1943-1945,1948,4.基金项目
上海市浦东新区社发局卫生科技基金资助项目(PW2006A-2). （PW2006A-2）
