重庆医学2013,Vol.42Issue(17):1957-1959,3.DOI:10.3969/j.issn.1671-8348.2013.17.011
18F-FDG PET/CT与MRT检测鼻咽癌颅底骨质浸润和靶区勾画的临床研究
Clinical research of MRI and 18F-FDG PET/CT in detecting and delineating target volume of skull base invasion in nasopharyngeal carcinoma
摘要
Abstract
Objective To evaluate the detective ability of magnetic resonance imaging (MRI) and positron emission tomography (PET) using 18-fluoro-2-deoxyglucose (FDG) PET/CT in skull base invasion in nasopharyngeal carcinoma.Methods 42 patients with nasopharyngeal carcinoma proved by pathology were examined by MRI and PET/CT which were performed at intervals ≤7 days.Results Of all the 42 patients,13 cases were positive in skull base invasion detected by MRI and PET/CT;6 cases were positive in MRI.but negative in PET/CT and 2 cases were positive only in PET/CT.There was no difference in two groups (P =0.289).The gross target volume delineated by PET/CT and by MRI (GTVP and GTVM) were compared.GTVP were smaller than their GTVM(P=0.0001).Conclusion The detection ability of PET/CT in skull base invasion in nasopharyngeal carcinoma is not superior to that of MRI.And because of false negative and leakage target,PET/CT can't replace MRI on delineation of target volume in nasopharyngeal carcinoma with skull base invasion.关键词
PET/CT/磁共振成像/鼻咽肿瘤/颅底浸润/靶区勾画Key words
PEC/CT / magnetic resonance imaging/ nasopharyngeal neoplasms / skull base invasion/ target volume delineation引用本文复制引用
罗树春,兰海涛,吴琦..18F-FDG PET/CT与MRT检测鼻咽癌颅底骨质浸润和靶区勾画的临床研究[J].重庆医学,2013,42(17):1957-1959,3.