重庆医学2013，Vol.42Issue(17)：1971-1972,1975,3.DOI:10.3969/j.issn.1671-8348.2013.17.016
重症肝病患者医院感染病原菌分布及耐药性研究
Distribution and drug resistance of pathogens in patients with severe hepatopathy complicated with nosocomial infection
邹菁华 1张琳 1肖静 1刘红娟1
作者信息
- 1. 重庆市九龙坡区第一人民医院消化科 400050
- 折叠
摘要
Abstract
Objective To investigate the distribution and resistance of nosocomial infection pathogens in patients with severe hepatopathy.Methods All the pathogenic bacteria isolated from clinical specimens of 486 hospitalized patients with severe hepatopathy from January 2008 to June 2012 were retrospectively analyzed.Results The incidence rate of nosocomial infection in severe hepatopathy patients was 24.9 ％ (121/486).158 strains of pathogens were isolated from 121 patients,among which 108 strains(68.4 ％) were gram-negative bacilli,37strains (23.4 ％) were gram-positive cocci,and 13 strains(8.2 ％) were fungi.Escherichia coli,coagulase negative Staphylococci and Klebsiella pneumonia were the three most common isolates.The resistance rates of Escherichia coli to ampicillin,ceftriaxone,ciprofloxacin,and cotrimoxazole were high,ranged from 44.6 ％ to 76.8 ％,but to Imipenem,amikacin,and Cefperazone-Sulbactam were lower,ranged from 0 ％ to 8.9 ％.14.3 ％ of Escherichia coli were extended-spectrum β-lactamase producing strains.The resistance rates of Staphylococcus to Penicillin and Erythromycin were higher,ranged from 66.7％ to 95.5 ％,while to Vancomycin and teicoplanin were low to 0 ％.Conclusion The incidence rate of nosocomial infection in severe hepatopathy is high.Escherichia coli and Staphylococci are the most prevalent strains,and had a higher resistance to common antibiotics.关键词
交叉感染/病原菌/抗药性/肝疾病Key words
cross infection / pathogen / drug resistance / liver diseases引用本文复制引用
邹菁华,张琳,肖静,刘红娟..重症肝病患者医院感染病原菌分布及耐药性研究[J].重庆医学,2013,42(17):1971-1972,1975,3.
