摘要
Abstract
Objective Analysis of acute brain injury in different degree and different period of time of blood glucose, insulin levels and the relationship between the serum levels of interleukin 6 (IL-6) content change and its clinical significance. Methods 106 cases of acute brain injury patients according to their GCS scores were divided into mild, moderate and severe group three, respectively, after injury in ID, 2D, 3D, 4D, 5D determination of fasting blood glucose, serum insulin values and calculated the insulin resistance index (HOMA-IR), analysis of acute craniocerebral injury degree and the relationship between HOM A-IR; using enzyme ELISA (ELISA ) method for the determination of the content of serum IL-6, according to the dynamic changes of IL-6, analysis of a-cute head injury severity and the content of serum IL-6 relationship. Results Different degree of acute craniocerebral injury patients blood glucose, insulin levels and HOMA-IR showed significant difference ( P＜0. 05 ), blood glucose, serum insulin and HOMA-IR higher,acute brain injury degree, while the content of serum IL-6 after injury in higher than that of control group (P＜0. 05 ), while in severe traumatic brain injury in hypertension was light and medium damage was more evident (P＜0. 05 ). Conclusion The fasting blood glucose, HOMA-IR and IL-6 in serum of acute brain injury degree and correlation, can be used as an assessment of acute head injury severity and prognosis in a objective index.关键词
颅脑损伤急性病/胰岛素抗药性/白细胞介素6Key words
craniocerebral trauma/ acute disease/ insulin resistance/ interleukin-6
