分析化学2013，Vol.41Issue(7)：1069-1073,5.DOI:10.3724/SP.J.1096.2013.21067
加速溶剂/固液固萃取-气相色谱/质谱法分析卷烟烟气中苯并[a]芘
Analysis of Benzo [a] pyrene in Tobacco Cigarette Smoke by Accelerated Solvent/Solid-Liquid-Solid Extraction Coupled with Gas Chromatography/Mass Spectrometry
摘要
Abstract
A novel sample preparation method for trace benzo[a] pyrene (BaP) in tobacco cigarette smoke by accelerated solvent/solid-liquid-solid extraction (AS/SLSE) has been developed,which integrated extraction and purification in one step.The tobacco cigarette samples were trapped,then extracted and purified by AS/SLSE.The extracts were concentrated before analysis by chromatography.The extraction conditions such as adsorbents,extraction temperature,flush volume,static extraction time and static cycles,were optimized.Under the optimized condition (5 g silicon magnesium sorbent,extraction temperature at 100 ℃,flush volume of 40％,static extraction time of 3 min and for 2 static cycles,the extraction process was repeated three times),the limit of detection was 1.0 μg/L and the average recovery was 97.1％ for determination of benzo [a] pyrene in tobacco cigarette smoke by AS/SLSE coupled with gas chromatography/mass spectrometry (GC/MS).The relative standard deviation was 2.5％.The developed method was successfully applied to the analysis of tobacco cigarette smoke sample,the analytical results accord with those obtained by current national standards recommended method.关键词
加速溶剂/固液固萃取/气相色谱/质谱法/卷烟烟气/苯并[a]芘Key words
Accelerated solvent/solid-liquid-solid extraction/ Gas chromatography/mass spectrometry/Tobacco cigarette smoke/ Benzo [a] pyrene引用本文复制引用
王春兰,汪军霞,胡静,胡玉玲,李攻科..加速溶剂/固液固萃取-气相色谱/质谱法分析卷烟烟气中苯并[a]芘[J].分析化学,2013,41(7):1069-1073,5.基金项目
本文系广东中烟工业有限责任公司科技计划项目(No.粤烟工[2010]科字第025号)资助 （No.粤烟工[2010]科字第025号）
