摘要
Abstract
Objective To investigate the genetic polymorphisms of 16 non-CODIS loci (D6S477,D22-GATA 198B05,D15S659,D8S1132,D3S3045,D17S1290,D14S608,D2S441,D18S535,D13S325,D10S1435,D11S2368,D1S1656,D7S3048,D10S1248 and D19S253) in Beijing Han population.Methods The DNA of 300 unrelated individuals in Beijing Han population were PCR amplified using GoldeneyeTM DNA identification system 18NC kit,and the PCR products were analyzed by electrophoresis through 3130XL genetic analyzer.The fragment sizes of alleles were taken subsequently by GeneMapper v3.2.Results The distributions of genotype frequencies of 16 non-CODIS STR loci in Beijing Han population satisfied the Hardy-Weinberg equilibration.The population genetic parameters were obtained as followings:heterozygosity was 0.677-0.873; discrimination power,0.890-0.967; probability of paternity exclusion,0.393-0.741; and polymorphism information content,0.706-0.853.Conclusion These 16 non-CODIS STR loci show great genetic polymorphisms in Beijing Han population,and are useful for the research of population genetics and forensic application.关键词
法医遗传学/多态现象,遗传/短串联重复序列/汉族Key words
forensic genetics/ polymorphism, genetic/ short random repeats/ Han nationality分类
社会科学
