国际医药卫生导报2013，Vol.19Issue(9)：1319-1321,3.DOI:10.3760/cma.j.issn.1007-1245.2013.09.038
枸橼酸钠抗凝在危重患者连续性血液净化治疗中的应用
Application of anticoagulation with sodium citrate in continuous blood purification for critically ill patients
摘要
Abstract
Objective To assess the safety and efficacy of anticoagulation with sodium citrate in continuous blood purification for critically ill patients.Methods 61 patients were randomly divided into sodium citrate group (n =38) and heparin group (control group,n =23).Both groups received continuous blood purification.Activated clotting time (ACT) and levels of Ca,Na+,urea nitrogen,and creatinine were determined; coagulation in extracorporeal circulation was observed.Results ACT was markedly prolonged after hemofiltion in RCA group as compared with the baseline (P＜0.05).ACT was significantly longer in the control group than in RCA group after treatment (P＜0.05).The filter clotting grading and the clotting grading of venous pot were significantly better in RCT group than in the control group (P＜0.05).pH,Na+ and HCO3-1 had no significance in RCA group before and after treatment (P＞0.05).Cr,BUN were significantly lower after treatment (P＜0.05).BUN was significantly decreased.Conclusions Topical sodium citrate anticoagulation for patients undergoing continuous blood purification is efficacious and has fewer complications.It is worth popularizing.关键词
枸橼酸钠/血液净化/抗凝Key words
Sodium citrate/Blood purification/Anticoagulant therapy引用本文复制引用
马月丹,苏俊权,徐优凤..枸橼酸钠抗凝在危重患者连续性血液净化治疗中的应用[J].国际医药卫生导报,2013,19(9):1319-1321,3.
