中国妇幼健康研究2013，Vol.24Issue(3)：366-368,3.DOI:10.3969/j.issn.1673-5293.2013.03.033
薄层液基细胞学检查对宫颈病变的诊断价值
Value of TCT in diagnosis of cervical precancerous lesions
摘要
Abstract
Objective To assess the value of thin-prep cytology test (TCT) in diagnosis of cervical precancerous lesions . Methods From April 2010 to March 2012, 3 590 patients performed TCT in Gynecology Department of First People 's Hospital of Jiande , and the Bethesda system (TBS) was used to report outcomes. There were 360 cases with abnormal outcomes, and 221 of them accepted biopsy under colposcopy. Results In 221 cases accepting biopsy , there were 56 cases of cervical intraepithelial neoplasia (CIN) Ⅰ, 55 cases of CIN Ⅱ/ Ⅲ and 6 cases of squamous cell carcinoma ( SCC). The coincidence rate of cytology and colposcopy biopsy results was 51. 56% ( 33/64) for low grade squamous intraepithelial lesion ( LSIL) , 73.91% ( 34/46 ) for high grade squamous intraepithelial lesion ( HSIL) , and 83. 33% (5/6) for SCC respectively. Among 105 cases of ASCIIS showed by cytology , 19. 05% were diagnosed with abnormity by biopsy (20 cases, 12 of CIN Ⅰ and 8 of CIN Ⅱ/Ⅲ). The Kappa value of TCT and biopsy was 0. 646 (P < 0. 01 ). The sensitivity and specificity of TCT was 82.90% and 81.73% , respectively. Conclusion TCT has high clinical value in diagnosis of cervical precancerous lesions and cervical carcinoma screening .关键词
阴道镜/薄层液基细胞学检查/宫颈上皮内瘤变/宫颈癌筛查Key words
colposcopy/ thin-prep cytology test (TCT) / cervical intraepithelial neoplasia (CIN) / cervical carcinoma screening分类
医药卫生引用本文复制引用
孔建平,罗柳珍..薄层液基细胞学检查对宫颈病变的诊断价值[J].中国妇幼健康研究,2013,24(3):366-368,3.基金项目
浙江省基金课题,浙江省建德市科技局资助项目(2010G07) （2010G07）
