中医学报2013,Vol.28Issue(7):1060-1061,2.
中西医治疗帕金森病抑郁症的临床研究
Clinical Research of the Improvement of Parkinson Depression by Traditional Chinese Medicine
摘要
Abstract
Objective:To explore the clinical curative effect of traditional Chinese medicine treatment for Parkinson depression.Methods:60 patients with Parkinson disease were divided into TCM treatment group and control group according to random number table method.The control group was given Madopar piece 0.125 ~ 0.250 g,3 times a day,Paroxetine 20 mg,once daily.The treatment group was given Chinese medicine dialectical treatment based on the control group.Use unified Parkinson disease rating scale(UPDRS) to assess severity degree and Hamilton depressive scale(HAMD) to assess depression severity before and after 8 weeks treatment.Results:The UPDRS and HAMD scores in Chinese medicine treatment group were decreased significantly after 8 weeks treatment.The total effective rate of antidepressant effect in TCM treatment group was obviously higher than that in routine drug treatment group.Conclusion:Chinese medicine treatment in treating PD patients with depression can effectively improve dyskinesia as well as depressive symptoms.关键词
帕金森病/抑郁症/美多巴片/帕罗西汀Key words
Parkinson disease / depression/ madopar piece/ paroxetine分类
医药卫生引用本文复制引用
刘璇,薛红,刘红敏..中西医治疗帕金森病抑郁症的临床研究[J].中医学报,2013,28(7):1060-1061,2.基金项目
深圳市科技计划项目(编号:201003175) (编号:201003175)