华西口腔医学杂志2013，Vol.31Issue(3)：267-271,5.DOI:10.7518/hxkq.2013.03.012
地塞米松冠周注射预防下颌阻生第三磨牙拔除后肿胀及张口受限的系统评价
Systematic review on control of swelling and trismus after extraction of impacted mandibular third molar by Dexamethasone pericoronal injection
李春洁 1赵洪伟 1李龙江 1李双君 1武媛 1廖学娟 1潘剑1
作者信息
- 1. 口腔疾病研究国家重点实验室华西口腔医院口腔颌面外科门诊(四川大学),成都610041
- 折叠
摘要
Abstract
Objective To assess the efficacy of Dexamethasone(DM) pericoronal injection for the control of swelling and trismus caused by impacted mandibular third molars extraction.Methods Cochrane,PUBMED,EMBASE and CBM were searched for eligible studies.Hand-searching included references of the included studies and Chinese dental journals.Risk of bias of the included studies was assessed by two reviewers independently using Cochrane Collaboration's tool,and data extraction was done by them.Meta-analysis was delivered with Revman5.1.Results Seven randomized controlled trials,involving 684 participants,were included.Six of them had moderate risk of bias and one had high risk of bias.Meta-analysis showed that DM pericoronal injection could relieve trismus by 6.77 mm (P=0.02)within 1-2 days after the surgery.It could also reduce 51％ of the risk of moderate-severe trismus(P＜0.00001) and could significantly control facial swelling (P＜0.05).There was no differences between 4 mg and 8 mg DM (P＞0.05).Conclusion Periodontal injection of 4-5 mg DM could control facial swelling and trismus following impacted mandibular third molar extraction.But more randomized controlled trials are needed.关键词
阻生牙/拔牙/地塞米松/Meta分析/系统评价Key words
impacted tooth/tooth extraction/Dexamethasone/Meta-analysis/systematic review分类
医药卫生引用本文复制引用
李春洁,赵洪伟,李龙江,李双君,武媛,廖学娟,潘剑..地塞米松冠周注射预防下颌阻生第三磨牙拔除后肿胀及张口受限的系统评价[J].华西口腔医学杂志,2013,31(3):267-271,5.
