江苏大学学报（医学版）2013，Vol.23Issue(1)：78-81,4.
中国汉族女性血清脂联素水平与乳腺癌关系的Meta分析
Meta-analysis: serum adiponectin level and breast cancer risk in Chinese Han women
摘要
Abstract
Objective:To evaluate the association of serum adiponectin concentration with breast cancer risk in Chinese Han women.Methods:Related papers about the association of serum adiponectin concentration with breast cancer risk in Chinese Han women published between 1995 and 2012 were retrieved and evaluated.Data were re-analyzed by Meta analysis.Results:A total of eight studies that meet the inclusion/exclusion criteria were included.Data from 481 cases of breast cancer and 346 healthy control subjects were analyzed.The results showed,① Patients with breast cancer had lower serum adiponectin values than healthy controls(P ＜ 0.05,WMD =-2.412,95％ CI-3.173 to-1.651).Among premenopausal women,patients with breast cancer also had lower serum adiponectin values than healthy controls (P ＜ 0.05,WMD =-1.884,95％ CI-2.770 to-0.998).② Compared with patients without lymph node metastasis,patients with lymph node metastasis had significantly lower serum adiponectin levels (P =0.002,WMD =-1.981,95 ％ CI-3.238 to-0.724).Conclusion:Lower adiponectin concentration could be a risk factor of breast cancer and a predictor of poor prognosis.关键词
Meta分析/乳腺癌/脂联素Key words
Meta analysis / adiponectin / breast cancer分类
医药卫生引用本文复制引用
叶菁菁,贾珏,董嗣婧,张彩丽,陈军建,袁国跃..中国汉族女性血清脂联素水平与乳腺癌关系的Meta分析[J].江苏大学学报（医学版）,2013,23(1):78-81,4.基金项目
江苏省自然科学基金资助项目(BK2009208) （BK2009208）
江苏省卫生厅国际交流支撑计划及面上科技项目(H201247) （H201247）
镇江市社会发展基金项目(SH2012027) （SH2012027）
镇江市医学重点人才项目(2010) （2010）
