昆明医科大学学报2013,Vol.34Issue(5):117-120,4.
血流储备分数测定在多支多处冠状动脉病变的应用
Application of Fraction Flow Reserve Measurement on Multi-vessel Coronary Artery Disease
李飞 1孙红梅 1高峰 1杜日映1
作者信息
- 1. 延安大学附属医院心内科,陕西延安716000
- 折叠
摘要
Abstract
Objective To investigate the value of myocardial fractional flow reserve (FFR) measured by pressure wire to assess the multi-vessel intermediate coronary artery stenosis.Methods 34 patients with 82 lesions multi-vessel intermediate coronary stenosis (50% to 70% stenosis) diagnosed by coronary angiography,were divided into two groups randomly:treatment of percutaneous coronary intervention (PCI) guided by FFR and treatment of routine PCI.And the former was treated with interventional therapy and drug therapy according to FFR value < 0.75 and FFR ≥ 0.75,respectively.The latter was treated with interventional therapy according to the results of angiography.Results There was no significant differences in degree of coronary artery disease between the two groups.The FFR group had a total of 39 stenosis,and 4 patients were treated by coronary intervention with inserting 7 stents.The control group had a total of 43 stenosis,and 11 patients treated by coronary intervention with inserting 22 stents.There was a significant difference (P < 0.05).After 3 months of follow-up,we found that there was a significant difference of patients with angina pectoris incidences (0.13% vs 0.44%,P < 0.05) in two groups.Conclusion Compared with conventional treatment,the patients with multi-vessel coronary artery disease treated with PCI guided by FFR,the numbers of implanted stent and vessels treated,angina occurrence reduced significantly,and the hospitalization costs decreased as well.关键词
压力导丝/冠脉造影/心肌血流储备分数/冠状动脉多支多处病变Key words
Pressure wire/ Coronary angiography/ Myocardial fractional flow reserve/ Multi-vessel coronary artery disease分类
医药卫生引用本文复制引用
李飞,孙红梅,高峰,杜日映..血流储备分数测定在多支多处冠状动脉病变的应用[J].昆明医科大学学报,2013,34(5):117-120,4.