临床神经病学杂志2013，Vol.26Issue(3)：225-227,3.
肉毒杆菌中毒的临床特点
Clinical features of botulism
摘要
Abstract
Objective To explore the clinical features of botulism.Methods The clinical data of 5 patients with botulism were retrospectively analyzed.Results All the five cases were onset due to take homemade stinky tofu,and among them three cases were in a collectivity food poisoning.The mean latency was 3.4 days.Initial symptoms were slurred speech 3 cases,dysphagia 3 cases,dizziness 3 cases,fatigue and diarrhea 2 cases respectively,while dyspnea and poor appetite 1 case.As the disease progressed,all 5 cases experienced dizziness and blurred vision,and occurred ptosis,ophthalmoplegia and generalized weakness 4 cases,chest distress,dyspnea and diplopia 3 cases.Botulinum antitoxins A and B were given after confirmation of the diagnosis,symptomatic therapies including oxygen inhalation,anti-infection,maintenance of hydroelectrolytic equilibrium etc.were applied as well.Finally,4 cases were significantly improved,however,two of them remained mild dysphagia,and the rest 1 case was no effective (the treatment was late).Conclusions The symptoms of nervous system damage are occurred in patients with botulism.Dizziness,cerebral nerves and muscle palsy are its main manifestations.Early application of botulinum antitoxins treatment is effectual.关键词
肉毒杆菌中毒/肉毒抗毒素/临床特点Key words
botulism / botulinum antitoxins / clinical features分类
医药卫生引用本文复制引用
买买提依明,马卫英,热西旦,颜静,杨宛霖,傅毅,陈生弟..肉毒杆菌中毒的临床特点[J].临床神经病学杂志,2013,26(3):225-227,3.基金项目
上海市自然科学基金面上项目(12ZR1418600) （12ZR1418600）
