临床神经外科杂志2013，Vol.10Issue(3)：136-138,3.DOI:10.3969/j.issn.1672-7770.2013.03.003
脑深部刺激手术技术要点探讨
Key points of deep brain stimulation surgery
摘要
Abstract
Objective To potentially improve the curative effect and reduce the complications of deep brain stimulation (DBS) by summarizing the key points during the procedure of DBS surgery.Methods 222 patients (116 male and 106 female) underwent DBS surgery in our department from March 2000 to October 2011,including 207 Parkinson' s disease (PD),5essential tremor and 10 dystonia.335 electrodes were implanted in 3 different targets including subthalamic nucleus (n =325),ventralis intermedius nucleus (n =14) and globus pallidus internus (n =16).The key points of the procedure were summarized as below:Sharp incised the arachnoid and piamater on a gyrus,appropriate microelectrode recording,an intraoperative MRI scan with CRW stereotactic frame,implanted the connectors in the bone grooves on occipital bone and fixed the IPG on the clavicle bone.Results During the follow-up at 1 year,3 year and 5 year,the improvement rate of Unified Parkinson' s disease rating scale part Ⅲ (UPDRS Ⅲ) at “off” state were 55.8％,53.4％ and 45.2％ respectively,and at “on” state were 22.5％,23.2％ and 20.4％ respectively.The complications included asymptomatic cortical hemorrhage,electrodes deeper than anticipation and postoperative incisional infections.Conclusion Meticulous mastering intraoperative surgical technique key points can improve the efficacy of DBS treatment and reduce the complications.关键词
脑深部刺激/手术技术/帕金森病/丘脑底核Key words
deep brain stimulation /surgical technique /Parkinson' s disease /subthalamic nucleus分类
医药卫生引用本文复制引用
吴曦,陈剑春,胡小吾,郝斌,梁晋川,周晓平,姜秀峰,戴冬伟,刘建民..脑深部刺激手术技术要点探讨[J].临床神经外科杂志,2013,10(3):136-138,3.基金项目
上海市科学技术委员会重点科技攻关专项(10411954400) （10411954400）
