临床神经外科杂志2013，Vol.10Issue(3)：174-175,178,3.DOI:10.3969/j.issn.1672-7770.2013.03.016
靶控输注瑞芬太尼-丙泊酚麻醉在癫痫手术的应用效果及对皮质脑电监测的影响
Comparison study on anesthesia methods during lumpectomy for epilepsy
李志华 1马明轩 1李云林 2王立红 1边晶3
作者信息
- 1. 067000 河北省承德市中医院
- 2. 北京市海淀医院功能神经外科
- 3. 承德市中心医院
- 折叠
摘要
Abstract
Objective To compare the anaesthesia effect and the effect of the exact localization with different anesthesia methods in lumpectomy with pinpointing the focus of epilepsy.Methods Ninty patients with temporal lobe epilepsy (aged-years,ASAⅠ-Ⅱ)scheduled for epilepsy foci resection with electrocoticography (ECoG) were randomly assigned to three groups including those receiving remifentanil-propofol TCI intravenous anesthesia (groupⅠ),sevoflurane inhalation anesthesia (groupⅡ) and sevoflurane combined propofol and remifentanil anesthesia (group Ⅲ).Anesthesia effect and the effect of the exact localization with different anesthesia methods in the epilepsy foci resection were observed.Results HR and MAP of three groups at every time point were not significant changed.the time of detectable electrocorticography,spontaneous breathing recovery and eye opening in group Ⅰ was significantly shorter than that in group Ⅱ and group Ⅲ.The wave of ECoG in group Ⅰ was not significant changed,but the frequencies of spike wave,αwave,β wave and δwave in group Ⅱ were reduced significantly compared to those in group Ⅰ.The frequencies ofαwave andβwave in group Ⅲ were reduced significantly compared to those in group Ⅰ.Conclusion TCI of remifentanil-propofol can be used as a good choice of anesthesia for the patients undergoing epileptic foci resection.It could keep anesthesia smoothly,speed up but not disturb electrocorticography detection,and make patients quickly and completely recover from anesthesia.关键词
靶控输注/麻醉/致痫灶/皮质脑电监测/外科手术Key words
TCI / anesthesia/ EcoG / epileptogenic zone / surgical procedures分类
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李志华,马明轩,李云林,王立红,边晶..靶控输注瑞芬太尼-丙泊酚麻醉在癫痫手术的应用效果及对皮质脑电监测的影响[J].临床神经外科杂志,2013,10(3):174-175,178,3.
