临床误诊误治2013,Vol.26Issue(6):61-64,4.DOI:10.3969/j.issn.1002-3429.2013.06.028
准分子激光与高能紫外光治疗儿童白癜风的对比观察
Comparative Study of Excimer Laser and High-energy Ultraviolet Light in Treatment of Children with Vitiligo
摘要
Abstract
Objective To evaluate the efficacy and safety of 308 nm excimer laser and high-energy ultraviolet light in treatment of children with vitiligo.Methods A total of 90 children (aged 4 ~ 14) with vitiligo (308 lesions),and each patient had more than 3 lesions at same parts of the body.A self-comparison method was used:one lesion was treated with 308 nm excimer laser,the second lesion was treated with high-energy ultraviolet light,and the third lesion was as control group.All lesions were treated with twice a week for 15 weeks.Efficacy was evaluated by the degree of pigment recovery after treatment.Results Excellence rates were 84.9% in 308 nm excimer laser group,and 66.7% in high-energy uhraviolet light group respectively; the differences were statistically significant (P < 0.05).Excellence rate of face-neck area was the highest of the two methods,and its curative effect was significantly better than those of other areas (P <0.05).Conclusion Both 308 nm excimer laser and high-energy ultraviolet light in treatment of children with vitiligo may achieve satisfactory efficacy.308 nm excimer laser therapy may be more effective in recovery rate and excellence rate with less adverse effects,but efficacy is related to the lesion positions.关键词
光疗法/准分子激光/高能紫外光/儿童/白癜风Key words
Phototherapy/ Excimer laser: High-energy ultraviolet light/ Childhood/ Vitiligo分类
医药卫生引用本文复制引用
杨雅方,刘永斌,单云辉,王莹,秦鹏,武海恩,马天琪,张欣,宋丽新..准分子激光与高能紫外光治疗儿童白癜风的对比观察[J].临床误诊误治,2013,26(6):61-64,4.基金项目
辽宁省自然科学基金资助项目(20092092) (20092092)