中国临床保健杂志2013,Vol.16Issue(3):263-265,后插2,4.DOI:10.3969/J.issn.1672-6790.2013.03.015
脑钠肽水平在慢性阻塞性肺疾病急性加重期和左心功能不全患者中的临床意义
The clinical significance of serum brain natriuretic peptide in patients with acute exacerbation of chronic obstructive pulmonary disease and patients with left ventricular dysfunction
刘辉 1徐晓玲1
作者信息
- 1. 安徽医科大学附属省立医院、安徽省立医院呼吸内科,合肥230001
- 折叠
摘要
Abstract
Objective To study the clinical significance of serun brain natriuretic peptide change in patients with acute exacerbation of chronic obstructive pulmonary disease and patients with left ventricular dysfunction.Methods Retrospective medical records analysis of all patients hospitalized from January 2008 to May 2011 with the final diagnosis of acute exacerbation of COPD and left ventricular dysfunction,and who had undergone serum BNP test at admission.Results The serum BNP levels in patients with left ventricular dysfunction was significantly higher than patients with COPD (P < 0.01).BNP levels were negatively correlated with FEV1 (% of predicted value,r =-0.868,P < 0.001).BNP levels were negatively correlated with LVEF (r =-0.868,P < 0.001).BNP > 200pg/ml,the number of patients with left ventricular dysfunction was greater than that of patients with COPD.Conclusion The serun BNP detection can help physicians in identifying heart failure in patients suffering from an acute exacerbation of COPD.关键词
肺疾病,慢性阻塞性/心室功能障碍,左/利钠肽,脑Key words
Pulmonary disease, chronic obstructive /Ventricular dysfunction,left/ Natriuretic peptide, brain分类
医药卫生引用本文复制引用
刘辉,徐晓玲..脑钠肽水平在慢性阻塞性肺疾病急性加重期和左心功能不全患者中的临床意义[J].中国临床保健杂志,2013,16(3):263-265,后插2,4.