国际眼科杂志2013，Vol.13Issue(7)：1452-1454,3.DOI:10.3980/j.issn.1672-5123.2013.07.46
小牛血去蛋白提取物对翼状胬肉术后干眼的影响
The influence of protein free calf blood extract eye gel on dry eye after pterygium surgery
摘要
Abstract
AIM: To investigate the influence of protein free calf blood extract eye gel on dry eye after pterygium surgery.METHODS: Thirty six patients (40 eyes) with primary nasal pterygium were enrolled in this study, which were divided into study group and control group randomly, with 20 eyes in each group. All patients received pterygium excision and limbal stem cell autograft surgery and tobramicin dexamethasone eye drops after surgery. Patients of the study group received protein free calf blood extract eye gel while those of the control group received 0. 1% sodium hyaluronate eye drops furthermore. Ocular surface disease index ( OSDI ) questionnaire, tear film break-up time (BUT) and Schirmer's I test I (Sit) were carried before and 3 months after surgery to evaluate the dry eye degree of the patients.RESULTS: There was no statistical difference between the age, gender and size of the pterygium of the study and control groups preoperatively. There was no statistical difference between the OSDI (2. 33 ±1. 02 vs 2. 32±0.93), BUT (8.80±2.48 us 8.35±2. 28) seconds and SI t (4. 30 ± 2. 30 vs 4. 40 ± 2. 44) of the two groups preoperatively. There was statistical difference between the OSDI (1.45±0.47 vs 1.81+0. 60), BUT (11.20±2.07 vs 9.50±2.40) seconds and S I t (8. 35±3.13 vs 6.35±2.18) of the two groups 3 months postoperatively, which was also different from that of the preoperative data correspondingly.CONCLUSION: Protein free calf blood extract eye gel could reduce the dry eye after pterygium surgery.关键词
翼状胬肉/干眼/手术/小牛血去蛋白提取物眼用凝胶Key words
pterygium/ dry eye/ surgery/ protein free calf blood extract eye gel引用本文复制引用
纪彩霓,李贵刚,费菲,郑鸿雁..小牛血去蛋白提取物对翼状胬肉术后干眼的影响[J].国际眼科杂志,2013,13(7):1452-1454,3.基金项目
国家自然科学青年基金(No.81200661) （No.81200661）
湖北省自然科学基金面上项目(No.2010CDB09802) （No.2010CDB09802）
武汉市青年科技晨光计划项目(No.201150431124) （No.201150431124）
