世界中医药2013，Vol.8Issue(5)：530-534,5.DOI:10.3969/j.issn.1673-7202.2013.05.018
益气养阴、活血化瘀散结法治疗2型糖尿病肾病Ⅲ、Ⅳ期气阴两虚夹瘀型40例临床研究
Clinical Study on Supplementing qi and Nourishing yin, Promoting Blood Circulation and Removing Blood Stasis to Treat 40 Cases of Type 2 Diabetic Nephropathy(Ⅲ~Ⅳ) in Deficiency of qi and yin Combined with Blood Stasis Patients
摘要
Abstract
Objective:To evaluate the effectiveness of supplementing qi and nourishing yin , promoting blood circulation and removing blood stasis therapy in treating type 2 diabetic nephropathy. Methods: Forty patients of diabetic nephropathy were randomly divided into treatment group and control group in a proportion of 2:1. The treatment group applied supplementing qi and nourishing yin promoting blood circulation and removing blood stasis therapy , using the treatment formula including herbs of astragalus mongholicus , rehmanniae radix, prepared rhubarb , selfheal, panax pseudoginseng , winged euonymus , cornus, fructus Aurantii. Placebo was used in the control group. The treatment lasted for 12 weeks. The indexes of TCM syndrome score , MAU, 24 h urine protein quantitative, glycosylated hemoglobin , hepatic and renal functions , and blood-lipid before and after treatment were observed and analyzed . Results: The TCM syndrome score decreased in treatment group after taking medicine with a decline by weeks . Statistical difference was found after 8 weeks, and the total effective rate was 81.48% at the end of 12 weeks. Compared with pre-treatment and placebo group , urinary protein also decreased after treatment with a significant difference . Conclusion: The therapy of supplementing qi and nourishing yin , promoting blood circulation and removing blood stasis could improve the symptoms of patients with diabetic nephropathy ( Ⅲ ~ Ⅳ ) in deficiency of qi and yin combined with blood stasis , and prevent the aggravation of diabetic nephropathy in Ⅲ、 Ⅳ period. It could be recommended for TCM clinical use in treating EDN.关键词
糖尿病肾病/中医药疗法/气阴两虚夹瘀/益气养阴活血/化瘀散结Key words
Diabetic Nephropathy / Deficiency of qi and yin combined with blood stasis / Supplementing qi and nourishing yin / Promoting blood circulation and removing blood stasis / Observation of clinical effect引用本文复制引用
高菁,李靖,莫士安,庄杰,来于..益气养阴、活血化瘀散结法治疗2型糖尿病肾病Ⅲ、Ⅳ期气阴两虚夹瘀型40例临床研究[J].世界中医药,2013,8(5):530-534,5.基金项目
本文章受北京市首都发展基金联合攻关课题"中医药治疗糖尿病肾病临床疗效评价方法的研究(编号:2005-SF-I-015)"的资助 （编号:2005-SF-I-015）
